Super-resolution quantum microscopy at the Heisenberg limit
Abstract
We introduce quantum microscopy by coincidence (QMC) featuring balanced pathlengths, which facilitates super-resolution imaging at the Heisenberg limit, drastically boosting speed and contrast-to-noise ratio (CNR) compared to existing wide-field quantum imaging methods. QMC uses correlated photons traversing symmetric paths, behaving like a photon with half the wavelength for twice the resolution. It withstands 155 times stronger stray light than classical signals, promising non-destructive bioimaging. Our approach propels quantum imaging to microscopic scale by imaging cancer cells. Experimental and theoretical results endorse this balanced pathlength configuration as a path to quantum-enhanced coincidence imaging at the Heisenberg limit.
Yide Zhang
NIH K99 Postdoctoral Fellow
My research is interdisciplinary and focused on developing new types of optical imaging techniques that could advance the work of other researchers and medical personnel in a wide variety of fields. Currently, I am developing next-generation photoacoustic and ultrafast imaging techniques that can observe biological and physical phenomena that are too fast to be imaged with existing methods. The observation of the ultrafast phenomena could provide a better understanding of the fundamentals of life and physical sciences. I am also developing novel quantum imaging approaches that can investigate biological organisms with an imaging performance that cannot be achieved using classical optical imaging. In my free time, I enjoy cooking, hiking, cycling, and traveling.