Simulation and experimental design of saturated excitation (SAX) multiphoton microscopy (MPM)

Abstract

SAX is modeled and found to generate irregular PSF containing spatial frequency content beyond the diffraction limit. No special chemistry and minimal modification of MPM is needed toward super-resolved fluorescence imaging in scattering media.

Publication
CLEO: Applications and Technology 2017, San Jose, California USA
Yide Zhang
Yide Zhang
Postdoctoral Fellow

My research is interdisciplinary and focused on developing new types of optical imaging techniques that could advance the work of other researchers and medical personnel in a wide variety of fields. Currently, I am developing next-generation photoacoustic and ultrafast imaging techniques that can observe biological and physical phenomena that are too fast to be imaged with existing methods. The observation of the ultrafast phenomena could provide a better understanding of the fundamentals of life and physical sciences. I am also developing novel quantum imaging approaches that can investigate biological organisms with an imaging performance that cannot be achieved using classical optical imaging. In my free time, I enjoy cooking, hiking, cycling, and traveling.

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