Highly stable two-photon oxygen imaging probe based on a ruthenium-complex encapsulated in a silica-coated nanomicelle

Abstract

A nanomicelle-based ruthenium-complex oxygen imaging probe is coated with a silica shell. The biostability of the silica-coated probe is improved by a factor of 4, while the oxygen-sensitivity is reduced by a factor of 3.

Publication
CLEO: Applications and Technology 2016, San Jose, California USA
Yide Zhang
Yide Zhang
NIH K99 Postdoctoral Fellow

My research is interdisciplinary and focused on developing new types of optical imaging techniques that could advance the work of other researchers and medical personnel in a wide variety of fields. Currently, I am developing next-generation photoacoustic and ultrafast imaging techniques that can observe biological and physical phenomena that are too fast to be imaged with existing methods. The observation of the ultrafast phenomena could provide a better understanding of the fundamentals of life and physical sciences. I am also developing novel quantum imaging approaches that can investigate biological organisms with an imaging performance that cannot be achieved using classical optical imaging. In my free time, I enjoy cooking, hiking, cycling, and traveling.

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