Theoretical analysis of the signal-to-noise ratio of two-photon oxygen imaging probes

Abstract

Signal-to-noise ratio performance of optical chemical sensors in the presence of phosphorescence saturation is described using Poisson statistics and Stern-Volmer kinetics. The described framework can be applied across a wide range of sensitivites and lifetimes.

Publication
Biomedical Optics 2016, Fort Lauderdale, Florida USA
Yide Zhang
Yide Zhang
Postdoctoral Fellow

My research is interdisciplinary and focused on developing new types of optical imaging techniques that could advance the work of other researchers and medical personnel in a wide variety of fields. Currently, I am developing next-generation photoacoustic and ultrafast imaging techniques that can observe biological and physical phenomena that are too fast to be imaged with existing methods. The observation of the ultrafast phenomena could provide a better understanding of the fundamentals of life and physical sciences. I am also developing novel quantum imaging approaches that can investigate biological organisms with an imaging performance that cannot be achieved using classical optical imaging. In my free time, I enjoy cooking, hiking, cycling, and traveling.

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